Electrochemical determination of atenolol and propranolol using a carbon paste sensor modified with natural ilmenite

Abstract In this study, a simple voltammetric method was reported for independent determination of propranolol (PROP) and atenolol (ATN) in pharmaceutical tablets using carbon paste electrode modified with natural Ilmenite (CPE-I). The analytical performance the sensor evaluated square wave voltammetry cyclic both ?(beta) blockers 0.1 mol L ?1 sulfuric acid solution (H 2 SO 4) . signal obtained H 4 showed good electrocatalytic activity toward oxidations PROP ATN compared bare one. enhanced oxidation peak current response can be attributed to catalytic effect ilmenite nanomaterial incorporated into electrode. Under optimal condition, linear calibration curves were ranging from 0.20 8.9 mmol 2.0 9.9 µmol ATN, detection limits 80 0.31 , respectively. CPE-I had repeatability reproducibility (RSD ? 3.2%) high sensitivity PROP. proposed applied these drugs tablets. results indicate that could an alternative routine quality control ? complex matrices.